Predictors for HCV treatment outcome: lower limit of quantification vs. limit of detection
نویسندگان
چکیده
منابع مشابه
Evaluation of Approximate Methods for Calculating the Limit of Detection and Limit of Quantification
In a previous paper, a computational method was presented for determining statistically rigorous limits of detection and quantification. The main purpose of this study is to evaluate similar but less computationally complex methods. These “approximate” methods use data at multiple spiking concentrations, are iterative, can be derived from either prediction intervals or statistical tolerance int...
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ABSTRACT Background and Objectives: Diagnosis of hepatitis E virus (HEV) infection could be missed in some cases if serological tests are used solely. Molecular characterization of HEV is essential for diagnosis of acute and chronic HEV infections, and evaluating the chronic HEV infection status in immunocompromised patients. T...
متن کاملLimit of blank, limit of detection and limit of quantitation.
* Limit of Blank (LoB), Limit of Detection (LoD), and Limit of Quantitation (LoQ) are terms used to describe the smallest concentration of a measurand that can be reliably measured by an analytical procedure. * LoB is the highest apparent analyte concentration expected to be found when replicates of a blank sample containing no analyte are tested. LoB = mean(blank) + 1.645(SD(blank)). * LoD is ...
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چکیده ندارد.
15 صفحه اولMethods to determine limit of detection and limit of quantification in quantitative real-time PCR (qPCR)
Quantitative Real-Time Polymerase Chain Reaction, better known as qPCR, is the most sensitive and specific technique we have for the detection of nucleic acids. Even though it has been around for more than 30 years and is preferred in research applications, it has yet to win broad acceptance in routine practice. This requires a means to unambiguously assess the performance of specific qPCR anal...
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ژورنال
عنوان ژورنال: MaRBLe
سال: 2016
ISSN: 2468-0311
DOI: 10.26481/marble.2014.v2.304